Electrochemical sensors and biosensors for the determination of diclofenac in pharmaceutical, biological and water samples


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Output type: Journal article review

UM6P affiliated Publication?: Yes

Author list: Boumya W., Taoufik N., Achak M., Bessbousse H., Elhalil A., Barka N.

Publication year: 2021

Journal: Talanta Open (2666-8319)

Volume number: 3

ISSN: 2666-8319

URL: https://www.scopus.com/inward/record.uri?eid=2-s2.0-85107292024&doi=10.1016%2fj.talo.2020.100026&partnerID=40&md5=bd344a913f4147219176c6e3baf73782

Languages: English (EN-GB)


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Abstract

Diclofenac is a non-steroidal anti-inflammatory drug of wide use around the world for the treatment of several diseases such as ankylosing spondylitis, acute muscle pain conditions, and osteoarthritis. Although in proper doses it does not display any side effects, an overdose of diclofenac can cause adverse effects in the human body. Moreover, the presence of diclofenac in ecosystems directly affects the health of living organisms, even if it is present at trace. Therefore, the development of analytical tools for diclofenac monitoring was needed. In this context, electrochemical sensing and biosensing methods have been commonly reported. In this review, a critical evaluation of the methods employed for diclofenac analysis is presented according to the following classifications: potentiometric sensors, sensing at non-modified solid electrodes, chemically modified electrodes and biosensors. Recent developments related to the use of electrochemical detection of diclofenac in pharmaceutical formulations, biological fluids and environmental samples were reported and discussed. © 2021


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Last updated on 2021-25-11 at 23:16